Wannanilistat

Wannanilistat foda Bayanan Basan

sunan	Ceilistat foda
Bayani	Grey Foda
CAS	282526-98-1
kima	≥99%
solubility	kusanluble cikin ruwa ko giya, mai narkewa a cikin Acetic acid, etyl ester.
kwayoyin Weight	316.31 g / mol
Marin Matsa	190-200 ° C
kwayoyin Formula	C25H39NO3
sashi	80-120mg
Storage na dan lokaci	Room Zazzabi
Grade	Takardar Pharmaceutical

 

Menene Ceilistat?

Ceilistat (CAS ba.282526-98-1) wanda aka fi sani da ATL-962, ATL 962 ko Citilistat magani ne da aka nuna don maganin kiba. Ana amfani dashi tare da ƙananan kalori, abinci mai ƙoshin mai, da motsa jiki mai dacewa don taimakawa cikin raunin nauyi.

Ana sayar da magungunan ƙwayoyin kiba a ƙarƙashin sunaye iri daban daban waɗanda suka haɗa da Ceislim,  Kilfat, Oblean, da Checkwt.

Ceilistat shine benzoxazine, mai hana maganin lipase wanda ke aiki da farko ta hana narkar da abinci da kuma shayar da mai.

 

Yaya Wannanilistat yana magance kiba?

Kiba ita ce babbar matsalar lafiyar jama'a a duniya a yau. Yana da rikitarwa, na yau da kullun tare da rikice-rikice da yawa wanda ke tattare da haɗuwar ƙwayar kitse mai yawa / adipose.

Kiba tana da alaƙa da rikicewar lafiya kamar su ciwon sukari na 2, hauhawar jini, hauhawar jini, yawan ƙwayar cholesterol, wasu cututtukan kansa, da kuma wasu cututtukan zuciya kamar su bugun jini da rashin lafiyar zuciya.

Kiba a cikin ƙasashe da yawa ya kai ƙarshen annoba don haka ya zama batun kula da lafiyar duniya.

Bincike ya nuna cewa asarar nauyi na 5 zuwa 10% na nauyin jikinka na farko na iya rage ƙwayoyin cuta masu nasaba da kiba.

Ceilistat ana daukarta a matsayin wakili mai hana kiba. Magungunan rigakafin kiba yawanci suna haɓaka kashe kuzari don haka asarar nauyi ta hanyar ƙa'idodin jiji da na rayuwa.

Ceilistat shine mai hana cututtukan ciki na hanji wanda ke da tasiri a cikin karatun ɗan adam.

Cetilistat tana aiki ta hanyar toshe narkar da abinci da kuma shan kitse a cikin abincin da kuke ci. Lokacin da kitse ba ya narkewa ana fitar da shi cikin najasa yayin motsin hanji. Yana aiwatar da wannan ta hanyar hana enzyme lipases da ke da alhakin lalata triglycerides (mai / kitse a jiki) a cikin hanji.

The tasirin cetilistat Don haka ana baje kolinsu a maganan ciki. Saboda haka yana nufin cewa cetilistat ta bambanta da sauran jami'ai masu hana kiba wadanda ke tasiri kwakwalwarka don rage yawan ci saboda yana aiki a gefe.

Lokacin da aka hana narkar da abinci da kuma shayar da mai, sanya kitsen mai ya iyakance saboda haka karancin kudin makamashi wanda ke haifar da asarar nauyi.

Kodayake, Cetilistat zai taimaka muku rage nauyi yana kanku don kula da ƙoshin abinci mai gina jiki mai rashi tare da motsa jiki don cin nasarar kiba mai nasara.

 

Cetilistat VS Orlistat

Dukansu cetilistat da jerin suna magunguna ne da aka yi amfani dasu don maganin kiba. Suna nuna irin wannan yanayin aikin wanda zasu sami asarar nauyi.

Ceilistat da jerin sunayen sune mai hana maganin ciki wanda ke hana ko rage narkewar abinci da kuma shayar da mai. Labaran lebe suna da alhakin lalata triglycerides a cikin hanji. Abubuwan da ba'a canza su ba ana maye gurbin su ta hanjin cikin hanjin mutum. Wannan aikin yana tabbatar da cewa ƙwayoyin basa cikin jiki wanda ke haifar da asarar nauyi.

An bayar da rahoton raguwar nauyi mai yawa a cikin cetilistat da jerin sunayen. Nasarar cetilistat vs orlistat ya dogara da salon rayuwarka kamar yadda suke bukatar ka tsaya ga mai karancin kalori mai gina jiki hade da motsa jiki na yau da kullun.

Ceilistat da kuma jerin sunayen suna nuna ingantaccen sarrafa glycemic kamar yadda aka nuna ta raguwa mai yawa a cikin haemoglobin plasma glycosylated. Hakanan suna rage haɗarin rikice-rikicen da ke da alaƙa da kiba kamar cututtukan zuciya, hawan jini, hauhawar matakan cholesterol, da kuma ciwon sukari na 2.

Abubuwan da ke faruwa na yau da kullun waɗanda ke haɗuwa da cetilistat da jerin sunayen sune tasirin cututtukan ciki yawanci saboda ƙwayoyin da basu canza ba. Koyaya, idan ka kwatanta cetilistat vs orlistat dangane da illolin da ke tattare da hakan, yawancin tasirin da ake samu suna da alaƙa da jerin sunayen fiye da na cetilistat. Bugu da kari, tsananin tasirin tasirin ya fi bayyana tare da jerin sunayen fiye da na cetilistat.

Lokacin kwatanta haƙuri na cetilistat vs orlistat, an bayar da rahoton cewa an yarda da cetilistat da kyau fiye da jerin sunayen.

An gudanar da bincike na makonni 12 wanda ya shafi marasa lafiya masu fama da ciwon sukari na 2 don tantance asarar nauyi, raguwa cikin haemoglobin na glycosylated, da kuma jure wa likitan ciki idan aka kwatanta da jerin sunayen. An haɗu da maganin tare da ƙarancin abinci mai ƙarancin matsakaici da ciwon sikari wanda aka sarrafa ta amfani da metformin.

Binciken ya gano cewa cetilistat da jerin sunayen sun rage nauyi sosai da kuma inganta glycemic control. Magungunan sun kuma rage haɗarin cuta na zuciya da jijiyoyin jini ta hanyar rage kewayen kugu wanda alama ce ta cututtukan zuciya.

A cikin wannan binciken, illolin da aka lura sune cututtukan ciki wadanda suka fi yawa tare da jerin sunayen, haka kuma tsananin tasirin abubuwan da ke tattare da jerin sunayen ya kasance ya fi na na ceelistat. Bambance-bambance a cikin tasirin cetilistat vs orlistat za a iya danganta su ga tsarinsu da bambancin sinadaran.

Cire janyewa daga binciken saboda sakamakon illa kuma sun kasance tare da jerin gwano fiye da na tsohuwar. Bugu da ƙari, cetilistat ya fi haƙuri fiye da jerin sunayen.

 

Wanene zai iya yi amfani da Ceilistat?

Kuna iya la'akari da shan Cetilistat (282526-98-1) idan kuna buƙatar rasa nauyi. Koyaya, kamar kowane irin magani, ɗauki matakan kariya yayin shan wannan magani.

An ba da shawarar Ceilistat ga mutanen da ke da yawan nauyin jikinsu (BMI) wanda ya fi 27. Haka kuma yana da kyau a ɗauki cetilistat idan BMI ɗinka ya fi 27 kuma kana fama da yanayin da ke tattare da kiba kamar su ciwon sukari da hauhawar jini. BMI manuni ne na kitsen jiki ta hanyar rarraba nauyi a cikin kilogram ta murabba'in tsawo a mita.

Idan ka zaɓi shan cetilistat, ka tabbata ka ɗauki maganin cetilistat daidai gwargwado tare da abincinka. Abubuwan da aka ƙayyade na likitan yara an fi dacewa da abinci, a cikin ko har zuwa awa ɗaya bayan cin abincinku.

Magungunan cetilistat yana faruwa a cikin kwantena ko tsarin kwamfutar hannu don gudanar da magana tare da gilashin ruwa. Hakanan zaka iya samun foda ceilistat. Maganin likitan da ya dace da tsawon lokacin magani za a ƙayyade ta hanyar mai ba da lafiyar ku dangane da yanayin da martani na farko game da shan magani.

Rashin nauyi a gida duk da haka ba a nuna fa'idodi ga yara ba, saboda haka kada ku ba wannan ga yara. Wannan yana kasancewa musamman tare da yara a lokacin balaga kamar yadda cetilistat na iya yin tasiri ga haɓakar su haka tare da tsayi.

Ceilistat ana daukarta mara lafiya ga mata masu ciki ko mata masu ƙoƙarin ɗaukar ciki. Zai iya haifar da haɗarin lafiya ga ɗan da ba a haifa ba.

An kuma shawarci uwaye masu shayarwa da su guji barna kamar yadda zai iya wucewa ga yaron.

Likitanku na iya ba ku shawara ku sha ko in ba haka ba ku guji cetilistat saboda wasu yanayin kiwon lafiya da ake ci gaba kamar su yawan jijiyoyin jiki, cholestasis (cututtukan hanta), da kuma ciwon malabsorption na yau da kullun.

 

Cetilistat sakamako masu illa

Ana ɗaukar foda ceil amintacce amma idan ka wuce sashin silsilar da aka ba da shawarar ko ka kasa bin umarnin da ka samu game da wasu illolin da ke faruwa. Wadannan illolin na iya faruwa a farkon amma suna da sauƙi kuma yakamata su tafi tare da ci gaba da amfani da miyagun ƙwayoyi. Idan basu tafi ba, ya kamata ka tuntuɓi likitanka.

Illolin illolin da ke tattare da cutarwa sune;

• Gas tare da fitarwa
• Maƙarar Nasal
• zawo
• ciwon kai
• Gaggawa da yawan hanji wanda zai iya zama da wuyar sarrafawa
• Mutuwar ta
• Man mai ko mai kitse

Hakanan wasu mawuyacin tasiri amma mafi munin sakamako mai illa na iya faruwa. Ya kamata ku tuntubi likitanku nan da nan lokacin da kuka lura da illa masu zuwa;

• Jaundice (raunin idanu ko duka jiki)
• Dark fitsari
• Rashin ci
• Gajiya ta ban mamaki
• Mai tsananin zafin ciki
• Matsalar haɗiye ko numfashi.

 

Cetilistat amfanin

Amfanin asarar nauyi na Ceilistat a cikin kulawar kiba shine babban amfani da aka san shi da shi. Amma duk da haka akwai wasu fa'idodin cetilistat waɗanda ke sa shi ya bambanta kuma ya fita waje tsakanin sauran magungunan asara.

Da ke ƙasa akwai wasu fa'idodi na gidan;

 

Taimaka muku ci gaba da rayuwa mai kyau ta hanyar asarar nauyi

Ceilistat ɗayan manyan magunguna ne masu raunin nauyi da kuma mai hana kiba. A cikin rayuwar ku ta yau da kullun samun nauyi mai yawa yana haifar da ƙaruwa a cikin girma da ƙoshin jiki galibi ana kiran su da yin kiba ko kiba. Sharuɗɗan biyu suna da alaƙa da al'amuran kiwon lafiya kamar su ciwon sukari na 2, cututtukan zuciya kamar bugun jini, hawan jini, da wasu cututtukan kansa kamar ciwon hanji da na mama.

Bambanci tsakanin masu kiba da masu kiba shine ma'aunin girman jiki (BMI). Ana daukar mutum mai nauyi in BMI ya fi girma ko daidai da 25 yayin da mai kiba ke da BMI sama da 30 ko kuma daidaita shi.

Shan cetilistat zai taimaka wa jikin ku don rage tarin ƙwayoyin cuta don haka kiyaye BMI mai kyau kuma saboda haka rayuwa mai kyau. Wannan haka yake domin yana saukar da damar yanayin barazanar rayuwa hade da kiba.

 

Yana taimakawa rage nauyi da rage haemoglobin glycosylated a cikin marasa lafiya masu ciwon sukari

Ciwon sukari da musamman keɓaɓɓun ciwon sukari na 2 wanda ake kira da ciwon sukari mellitus cuta ce ta gama gari a cikin marasa lafiya masu kiba. Rubuta ciwon sukari na 2 yana faruwa ne lokacin da ƙwayoyin jiki ke tsayayya da tasirin insulin, wanda shine ya jagoranci glucose na jini zuwa cikin sel. Wannan yana haifar da tarin glucose cikin jini. An san kiba yana ƙaruwa sosai ga kamuwa da ciwon sukari na 2.

Glycosylated haemoglobin (haemoglobin wanda glucose ke ɗaura) shine ma'auni na kula da ciwon sukari na dogon lokaci. Matsayin glymozynologi na haemoglobin (HbA1c) yana nuna matsakaicin glucose na jini a cikin watanni uku da suka gabata. Matsayin haemoglobin na glycosylated na yau da kullun shine 7% amma yawancin mutane da ciwon sukari zasu iya cimma kashi 9% kawai.

A cikin makon 12, bazuwar, nazarin asibiti tare da kulawar wuribo, an ba marasa lafiya masu kiba da ciwon sukari na 2 cetilistat (40, 80, ko 120mg sau uku kowace rana). Hakanan sun kasance suna manne da tsarin abincin hypocaloric. An gano Ceilistat don rage nauyi da kuma rage haemoglobin glycosylated (HbA1c). Hakanan an lura cewa an yarda da cetilistat sosai.

 

An yarda da Ceilistat sosai

Baya ga ingancin sa wajen rage nauyi da kuma kula da kiba, akwai sauran abubuwa akan sa. An yarda da Ceilistat a cikin jiki tare da larura masu sauƙi zuwa matsakaici waɗanda aka iya sarrafawa kuma suna iya ɓacewa tare da ci gaba da amfani da maƙerin.

Kodayake yawancinmu muna zuwa don amfani cikin magani, amma kuma yana da kyau mu nemi magani wanda za'a iya jurewa a jikinku.

A cikin nazarin asibiti na zamani na 2 an gudanar da shi na makonni 12 ta amfani da magungunan ta biyu da kuma jerin sunayen da ake samu. An gano magungunan biyu masu yin asara suna da tasiri wajen rage nauyi, rage haemoglobin glycosylated da kuma rage kewayen kugu. Hakanan, an gano cetilisat da juriya sosai fiye da jerin sunayen, tare da raunin raunin sakamako kaɗan da ƙasa da alaƙa da cetilistat.

 

Taimaka maka ka cimma burinka cikin kankanin lokaci

Rashin nauyi nauyi ne na ɗan gajeren lokaci wanda za a iya cimma ta hanyar canjin abinci da haɗuwa da motsa jiki na yau da kullun. Koyaya, kiyaye nauyin lafiya shine manufa ta dogon lokaci.

Kwararka na iya bayar da shawarar maganin asara na asara lokacin da salon rayuwa mai kyau (abinci da motsa jiki) ba su cimma asarar nauyi da aka nufa ba. Ceilistat na ɗaya daga cikin magungunan da za a iya amfani dasu tare da cin abinci mara ƙanshi da motsa jiki na yau da kullun. Ba kamar sauran magunguna masu hana kiba wadanda ke daukar lokaci mai tsawo don cimma babbar asara ba, cetilistat tana daukar kimanin makonni 12 don samar da nauyin da ake so.

 

Zai iya taimakawa rage matakin cholesterol

Cholesterol yana nufin wani abu mai ƙima. Jikinku yana buƙata don gina ƙwayoyin duk da haka, da yawa na iya haifar da lamuran cikin jiki.

Hanta ce ake yin ta ta hanta yayin da wasu ke zuwa daga abincin da kuka cinye kamar nama, kaji, da kayan kiwo mai cikakken mai. Akwai nau'ikan cholesterol iri biyu. -Ananan ƙwayar lipoprotein (LDL) cholesterol ko "mummunan" cholesterol da lipoprotein mai girma ko kuma "mai kyau" cholesterol. LDL yana ba da gudummawa ga haɓaka mai a cikin jijiyoyi don haka yana ƙara haɗarin cututtukan zuciya kamar su bugun jini da bugun zuciya.

Yin kiba yana ƙara haɗarin yawan matakan cholesterol. Kiba tana kara adadin cholesterol na LDL ta hanyar sauya martanin jikinka ga kitsen da kake ci. Kumburin da kiba ya haifar kuma yana rage martabar jikin ku ga canje-canje a cikin cin mai mai ƙoshin abinci. Bugu da ƙari, juriya na insulin ma galibi ne ga marasa lafiya da kiba. Wannan kuma yana shafar tsarin al'ada na kitse a jikinku.

Ceilistat na iya rage yawan cholesterol da LDL cholesterol.

A cikin wani binciken da ya shafi beraye, an gano cetilistat da ake gudanarwa da baki don inganta kiba da yawan cholesterol.

 

Rage haɗarin cutar zuciya da jijiyoyin jini

Cututtukan zuciya da jijiyoyin jini kalma ce gama gari da ke magana game da cuta da ta shafi zuciya ko jijiyoyin jini. Cututtukan zuciya da jijiyoyin jini sun haɗa da cututtukan jijiyoyin zuciya irin su bugun zuciya da angina, bugun jini, bugun zuciya, da cutar cututtukan zuciya da sauransu.

Dalilin cututtukan zuciya da jijiyoyin jini ya bambanta dangane da takamaiman cuta. Misali, cututtukan jijiyoyin jijiyoyin jini, bugun jini, da cututtukan jijiyoyin jiki na iya haifar da cutar hawan jini, da ciwon sukari na biyu, shan sigari, rashin motsa jiki, kiba, da rashin cin abinci. An kiyasta kiba don kimanin 2% na cututtukan zuciya da jijiyoyin jini.

Ceilistat, saboda haka, tana rage haɗarin kamuwa da cututtukan zuciya ta hanyar kula da kiba da ƙarfafa ingantaccen abinci wanda ke taka rawa wajen hana faruwar cututtukan zuciya.

A cikin mako 12 bazuwar, binciken makafi biyu wanda ya shafi marasa lafiya masu fama da ciwon sukari, an gudanar da maganin a 40, 80, ko 120 MG sau uku a kowace rana. An kuma shawarci mahalarta su ci abinci mara mai mai yawa a lokacin karatun.

Wannan binciken ya ba da rahoton raguwar nauyi kazalika da ingantaccen sarrafa glycemic. Bugu da kari, an sami raguwa sosai a kewayen kugu wanda daya daga cikin dalilan kasada a cikin cututtukan zuciya.

 

Zai iya rage hawan jini

Hawan jini wanda kuma ake kira da hauhawar jini wani yanayi ne wanda karfin jini akan bangon jijiyoyin ya kasance yana daukaka a wani lokaci. Hawan jini yana da haɗari saboda yana tilasta zuciya yin aiki tuƙuru wanda ke haifar da tauraron jijiyoyin.

Hauhawar jini na hade da wasu cututtukan da ke barazana ga rayuwa kamar su bugun jini, koda, da cututtukan hanta da sauransu.

Yin kiba ko kiba yana ɗaga damar samun hawan jini. Ruwan jininka yana ƙaruwa tare da ƙaruwa cikin nauyi.

Saboda haka, yana nufin cewa rasa nauyi yana ɗaya daga cikin hanyoyin da za a rage hawan jini. Anan ne cetilistat ta shigo saboda tana haifar da asarar nauyi mai yawa cikin kankanin lokaci.

 

Ina zan iya saya Cetilistat?

Idan kayi la'akari da amfani da cetilistat saya kan layi ta hanyar jin daɗin gidanka. Akwai foda ceilistat akan layi a cikin masu samar da kodinilistat ko masana'antun cetilistat Stores. CMOAPI ɗayan masana'antun cetilistat ne waɗanda ke siyar da samfuran inganci tare da kyakkyawan sabis na abokin ciniki.

Lokacin siyan foda ko inuwa idan ba haka ba daga CMOAPI ko wasu masu samar da kayan kwalliyar a hankali suna bincika alamun don amfani da miyagun ƙwayoyi. Yi la'akari da sashi na likitancin da aka ba da shawara kamar yadda mai sana'ar saƙo ya umurta amma kuma bi shawarwarin daga mai ba da lafiyar ku.

Reading sake duba tsarin daga kwarewar mutum na iya taimaka maka don samun kyakkyawar fahimta game da inganci da aminci. Mafi yawan kwastomomin cetilistat suna saya akan layi kuma suna iya barin sake nazarin cetilistat gwargwadon kwarewar su.

Farashin katako Shima abin la'akari ne lokacin da kake son siyan shi. CMOAPI yana ɗaya daga cikin masu samarda kayan kwalliyar kwalliya waɗanda zasu iya bayar da farashin gasa mai tsada. Koyaya, farashin cetilistat bazai makantar da ku don zaɓar samfurin ƙarancin inganci ba.

Saya daga jin daɗin gidanku na iya zama mai jan hankali don yin sayayya cikin sauri, duk da haka, har yanzu kuna buƙatar yin shiri yadda yakamata don sanin samuwar magungunan da kuke buƙata tukunna.

 

References

1. Bryson, A., de la Motte, S., & Dunk, C. (2009). Rage yawan shan mai mai narkewa ta hanyar maganin hana kutse mai lalata ciki a cikin masu sa kai na lafiya. Jaridar Burtaniya ta likitancin magunguna, 67(3), 309–315. https://doi.org/10.1111/j.1365-2125.2008.03311.x.
2. Hainer V. (2014). Bayani game da sababbin magungunan rigakafi. Kwararrun masanin ilimin likitancin magani, 15(14), 1975–1978. https://doi.org/10.1517/14656566.2014.946904.
3. Kopelman, P., Groot, G., Rissanen, A., Rossner, S., Toubro, S., Palmer, R., Hallam, R., Bryson, A., & Hickling, RI (2010). Rage nauyi, ragin HbA1c, da kuma jure yanayin cutar a cikin bazuwar, gwajin gwajin wuribo na 2 a cikin masu fama da ciwon sukari: kwatantawa da jerin sunayen (Xenical). Kiba (Faduwar Azurfa, Md.), 18(1), 108–115. https://doi.org/10.1038/oby.2009.155.
4. Kopelman, P; Bryson, A; Hickling, R; Rissanen, A; Rossner, S; Toubro, S; Valensi, P (2007). "Cetilistat (ATL-962), wani labari mai hana maganin lipase: Wani mako-mako bazuwar, nazarin-wuribo na rage nauyi a cikin marasa lafiya masu kiba". Jaridar Duniya ta Kiba. 12 (31): 3-494. Doi: 9 / sj.ijo.10.1038. PMID 0803446.
5. Jirgin, R (2008). "Cetilistat, sabon maganin hana kiba na maganin kiba". Ra'ayi na Yanzu game da Magungunan bincike. 9 (4): 414– PMID 18393108.
6. Yamada Y, Kato T, Ogino H, Ashina S, Kato K (2008). "Cetilistat (ATL-962), wani labari mai hana lalata lipase, yana inganta ƙimar jiki da inganta haɓakar lipid a cikin beraye". Binciken Hormone da na rayuwa. 40 (8): 539– doi: 10.1055 / s-2008-1076699. PMID 18500680. S2CID 29076657.

 

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