Tadalafil

CMOAPI yana da cikakken kayan albarkatun Tadalafil, kuma yana da tsarin gudanarwa mai inganci mai kyau.

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Menene Tadalafil

Tadalafil magani ne na likitanci da ake amfani dashi don magance matsalar rashin ƙarfi ta hanyar lalata (ED) da kuma alamun bayyanar karuwar prostate a cikin maza. Hakanan ana nuna shi don magance hauhawar jini na huhu (PAH).
Tadalafil (Lambar CAS: 171596-29-5) ana samunsa a cikin nau'i na kwamfutar hannu ta baka ko tadalafil foda kuma galibi ana siyar da ita a ƙarƙashin sunan Cialis (don ɓarna ko kuma haɓakar ƙanƙanin mara mai kyau) ko Adcirca (don hauhawar jini na huhu). Hakanan ana samun Tadalafil a cikin sifofinsa na yau da kullun wanda watakila bashi da dukkan ƙarfi kamar asalin asali


Ta yaya tadalafil ke aiki?

Tadalafil shine ɗayan masu hanawa na 5 (PDE5) na phosphodiesterase. Lokacin da waɗannan rukuni na kwayoyi suka hana PDE5 su kuma suna haɓaka aikin erectile.
Yayin motsawar sha'awa, tsagewar yana faruwa lokacin da isasshen jini ya gudana a jijiyoyin azzakarin da ke haifar da annashuwa da jijiyoyin tsoka na gawar jiki. Ana ba da wannan amsa ta hanyar samar da sinadarin nitric (NO) a cikin ƙwayoyin endothelial da ƙananan jijiyoyi. Sakin NO yana haɓaka kira na cyclic guanosine monophosphate (wanda aka fi sani da GMP na cyclic ko cGMP) a cikin ƙwayoyin tsoka masu santsi. GMP na cyclic yana taimakawa shakata da tsoka mai santsi kuma yana ƙaruwa da jini zuwa gaɓar gawar.
Tadalafil ya hana nau'in 5 (PDE5) na phosphodiesterase ta hanyar ƙara yawan cGMP. Yana da kyau a lura cewa dole ne mutum ya sami nutsuwa ta hanyar jima'i don ƙaddamar da sakin sifa na nitric oxide. Wannan saboda tasirin Tadalafil ba zai faru ba tare da motsawar jima'i ba.
Tadalafil na iya rage bayyanar cututtukan cututtukan glandan ciki wanda ya hada da saurin / yawan fitsari, wahalar yin fitsari, da rashin yin fitsari. Yana cimma wannan ta hanyar shakatawa tsokoki a cikin prostate da mafitsara.
A cikin hauhawar jini na huhu, tadalafil yana taimakawa shakatar da jijiyoyin jini a kirji. Wannan kuma yana taimakawa kara samar da jini ga huhu sannan kuma yana rage aikin zuciya.


Matsakaici na Tadalafil

A yayin samar da tadalafil (CAS 151596-29-5), an kafa wasu masu shiga tsakani. Wasu kamfanoni zasuyi amfani da tsaka-tsakin tadalafil don samar da tadalafil.

Cas 171596-29-5

Tadalafil (CAS 171596-29-5) magani ne mai iko da inganci don maganin raunin rashin ƙarfi da kuma ƙaruwa na karuwanci a cikin maza da kuma hauhawar jini na jijiyoyin jini.

Cas 171489-59-1

Cas 171489-59-1 wanda ake kira da Chloropretadalafil shine matsakaici a cikin samar da Tadalafil wanda aka yi amfani dashi don magance matsalar rashin ƙarfi. CAS 171489-59-1 yana da tsarin ƙirar C22H19ClN2O5 tare da nauyin kwayar 426.85 g / mol. Akwai shi a cikin sifofin farin farin.

Cas 171752-68-4

CAS 171752-68-4 wanda tsarin kwayar sa shine C20H18N2O4.HCl da nauyin kwayar 386.83 g / mol shima matsakaiciyar tadalafil ce.
Akwai masu samar da tadalafil masu yawa waɗanda ke ba da tsaka-tsakin tadalafil don siyarwa a farashi masu tsada. Koyaya, idan kayi la'akari da tadalafil siya daga kamfanoni masu amintattu don tabbatar da ingancin bai ƙunshi ba.
CMOAPI na ɗaya daga cikin masu samar da matsakaiciyar tadalafil waɗanda ke ba da tabbaci mai kyau da ƙimar farashin kayan su.


Wanene da yadda ake amfani da tadalafil

Tadalafil foda zai iya bi da waɗannan a cikin maza?

Erectile dysfunction

Rashin lalata Erectile (ED) wanda ake kira rashin ƙarfi yanayi ne a cikin maza wanda ba sa iya samun ko ci gaba da gini don isasshen lokacin yin jima'i. Hakan yakan haifar da sha'awa ga jima'i kuma hakan na iya haifar da wasu rikice-rikice kamar saurin tsufa ko jinkirta saurin inzali da wani lokacin rashin samun damar isa ga inzali.
Ana iya haifar da ED ta dalilai da yawa na yanayin jiki da na motsin rai kamar wasu cututtuka kamar su ciwon sukari, cututtukan zuciya, da hauhawar jini, shekaru, damuwa, ko ma batun alaƙa.
Tadalafil yana taimakawa magance ED ta hanyar ƙara yawan jini zuwa azzakari. Wannan kuma yana taimakawa ci gaba da ci gaba da ginawa. Koyaya, tadalafil yana taimakawa kawai tare da kafa lokacin da mutum ya riga ya motsa da jima'i.

Cutar hyperplasia mai saurin rauni (BPH)

Hakanan ana kiransa da fadada gland na prostate, BPH wani yanayi ne na yau da kullun da akan samu ga maza yayin tsufan su. Koyaya, wasu dalilai da yawa na iya haifar da faɗaɗa prostate gami da ciwon sukari da cututtukan zuciya, salon rayuwa, da musamman kiba da kuma tarihin iyali na BPH. Lokacin da prostate ya kara girma zai iya haifar da yanayin fitsari.
Alamomin dake tattare da girman glandan prostate sune, gaggawa da saurin yin fitsari, samun wahalar fara yin fitsari, raunin fitsari mara karfi, ko kuma rashin fitarda mafitsara cikakke. Sauran alamun BPH na iya haɗawa da cutar yoyon fitsari (UTI), ba zai iya yin fitsari ba, ko jini a cikin fitsarin.
Tadalafil foda ko kwamfutar hannu na taimakawa shakata tsoka a cikin prostate da mafitsara. Wannan yana taimakawa saukaka alamun BPH.

Jijiyoyin jijiyoyin jini na jini (PAH)

PAH wani yanayi ne wanda a cikinsa akwai hawan jini a jijiyoyin da ke bayar da jini ga huhu. Ya bambanta da hawan jini na kowa. Yana faruwa ne yayin jijiyoyin daga zuciya zuwa huhu su zama kunkuntar ko kuma an toshe su.
Mafi yawan alamun bayyanar sun hada da ciwon kirji, gajiya, ko ma kumburi a ƙafafunku da idon sawu.
Tadalafil na iya taimakawa bayyanar cututtukan PAH ta hanyar kwantar da jijiyoyin jini a cikin huhu wanda hakan ke ƙara yawan jini.

Yaya ake amfani da tadalafil?

Tsarin tadalafil ya dogara ne akan shekarunka, amfani da shi, da duk wasu maganganun kiwon lafiya.
Ba a ba da shawarar yin amfani da Tadalafil ga yara 'yan ƙasa da shekaru 18 yayin da kuma shekarun da suka wuce shekaru 65 ya kamata su yi taka-tsantsan tun lokacin da jikinsu ya ɗauki tsawan lokacin shan waɗannan magungunan.
Akwai cikakkun jagororin kan yadda ake amfani da tadalafil foda amma mafi yawan nau'ikan tsari shine kwamfutar tadalafil karkashin wasu sunaye daban daban.
Yana da kyau a dauki tadalafil sau ɗaya a rana kuma a ɗauka a kusan lokaci ɗaya kowace rana don samun fa'idodin tadalafil.
An bayyana ma'anar tadalafil don amfani daban-daban;
Don rashin lahani, ana shan kashi na 2.5-5 MG kowace rana ko 10 MG idan aka sha sau ɗaya kamar yadda ake buƙata.
Don cutar hyperplasia mai saurin rauni, an ba da shawarar kashi 5 na MG da aka sha kowace rana. Tadalafil ya kamata a sha sau ɗaya kowace rana.
Lokacin ma'amala da sharuɗɗan duka (cutar daskararre da haɓaka prostate) samfurin 5 MG kowace rana ya dace.
Tare da hauhawar jini na jijiyoyin jini, an ba da shawarar tadalafil na 40 MG da ake ɗauka kowace rana.
Kamar sauran magunguna, abin da ke aiki ga ɗayan bazai yi wa wani haka ba. Akwai hanyoyin madadin Tadalafil. Koyaya, abu mafi kyau shine ayi magana da likitanka game da wadatattun hanyoyin tadalafil kuma ku ga wanda yafi dacewa da ku. Ana iya ba ku shawara ku ɗauki madadin tadalafil idan kuna rashin lafiyan tadalafil ko saboda wasu dalilai.
Hakkin ku ne ku lura da abin da ke aiki mai kyau a gare ku yayin da kuke yanke hukuncin tadalafil shine zaɓi ko sakamakon tasirin tadalafil ya biya fa'idodin tadalafil.


Menene banbanci tsakanin Tadalafil da sauran magunguna don rashin karfin erectile

Cialis (Tadalafil)

Cialis magani ne na likitanci a cikin ajin magungunan da ake kira Phosphodiesterase-5 Enzyme Inhibitors. Ana amfani da shi don magance alamun rashin lahani. Ana iya amfani dashi shi kaɗai ko a sa shi tare da sauran magunguna.

Dapoxetine Hydrochloride

Dapoxetine hydrochloride an kasafta shi azaman mai saurin zafin maganin serotonin reuptake inhibitors (SSRIs).
Dapoxetine hydrochloride magani ne mai rijista wanda ake amfani dashi don magance saurin inzali. Saurin inzali wani yanayi ne da ya zama ruwan dare ga maza wanda ya hada da rashin jinkirin fitar maniyyi. Wannan wata alama ce ta rashin karfin maza a cikin maza.
Kodayake ana amfani da tadalafil da dapoxetine hydrochloride don magance alamun rashin lahani, ɗayan tadalafil shine mai hana phosphodiesterase yayin da ɗayan, dapoxetine, shine mai zaɓin maganin serotonin reuptake.

Vardenafil Hydrochloride

Vardenafil magani ne a cikin rukuni na ƙwayoyi da ake kira masu hana haɓakar phosphodiesterase (PDE). Ana amfani dashi don magance matsalar rashin karfin maza. Lokacin da namiji ya motsa da sha’awa, vardenafil yana ƙara yawan jini zuwa azzakari wanda hakan zai tabbatar maka da samun tsayuwa.
Vardenafil da aka siyar a ƙarƙashin sunan suna Levitra yana da zaɓi sosai fiye da sildenafil da tadalafil (Cialis) zuwa PDE5. Wannan yana nufin cewa ana buƙatar ƙaramin ƙwayar vardenafil tare da fewan tasirin da zai iya haifar.
Wani sanannen bambanci shine a cikin rabin rayuwa inda vardenafil (Levitra) ke da rabin rai na awanni 4-6 yayin da tadalafil (Cialis) ke da rabin rai na awanni 17.5. Wannan shine ma'anar cewa Tadalafil (Cialis) yayi aiki fiye da vardenafil.

Avanafil

Avanafil magani ne a cikin rukuni na masu hana phosphodiesterase. Hakanan ana amfani dashi don magance matsalar rashin karfin al'aura ta hanyar inganta yaduwar jini a yankin penile.
Kodayake duka avanafil da tadalafil sune masu hanawa na phosphodiesterase, avanafil shine mafi sabo kuma yana da ɗan gajeren rabin rayuwa na kusan awanni 5 fiye da tadalafil wanda yake da rabin rai na awa 17.5.
A ƙarshe, tadalafil ya fi kyau saboda tsawon rabin rayuwarsa. Mutum na iya shan magani tare da effectsan sakamako masu illa.


Tadalafil Sakamakon sakamako da fa'idodi

Fa'idodin Tadalafil

Mutane da yawa waɗanda suke yin la'akari da amfani da tadalafil foda suna saya saboda ainihin fa'idodin tadalafil;

Yin maganin rashin karfin erectile

Tsaran penile shine tsari mai mahimmanci don aikin jima'i. Rashin saurin lalata namiji yana faruwa yayin da namiji ya kasa samun karfin tsayuwa. Wannan yana haifar da lamura da yawa kamar damuwa, ƙarancin daraja, har ma da matsalolin alaƙa.
Ana samun karfin kafa lokacin da isasshen jini ke gudana a cikin azzakari. Tadalafil yana taimakawa sauƙaƙe alamun bayyanar rashin aiki ta hanyar ƙara yawan jini zuwa azzakari.

Kula da alamomin cutar rashin karfin jiki

Hakanan ana kiranta hyperplasia mai saurin karuwa a matsayin ƙara girman glandan. Wannan yanayin ne wanda ke faruwa a hankali tare da shekaru. Idan glandar prostate ta kara girma, takan matse fitsarin. Wasu daga cikin alamomin da ke alakantuwa da kara girman prostate sune; gaggawa da yawan fitsari, mai wahalar fara fitsari, fitsari mai raɗaɗi a tsakanin wasu.
Tadalafil yana amfani da maza masu fama da cutar hyperplasia ta prostatic ta hanyar sauƙaƙe waɗannan alamun. Tadalafil foda yana taimakawa shakatawa glandon prostate da mafitsara saboda haka yana rage alamun da ke tattare da matse mafitsara da mafitsara.

Za a iya bi da cutar daskararren mahaifa da hyperplasia mai saurin rauni

Tadalafil na iya taimaka wa maza da ke fama da rauni na rashin ƙarfi da kuma faɗaɗa glandar prostate lokaci guda.
Lokacin da kake amfani da tadalafil a madaidaicin sashi kuma kamar yadda aka ba da shawarar ka girbe fa'idodin da aka faɗi. Tunda na haɓaka yaɗuwar jini a cikin azzakarin yanki da ma wasu yankuna, hanya ce mai lafiya don magance waɗannan yanayin.

Hakanan za'a iya amfani dashi wajen magance cututtukan jini na jijiyar jini

Rashin jini na jijiyoyin jini (PAH) yana nufin cewa akwai hawan jini a jijiyoyin da ke daukar jini daga zuciya zuwa huhu. Duk da haka ya banbanta da hawan jini na yau da kullun.
PAH na faruwa ne yayin jijiyoyin da ke bada jini zuwa huhu ya zama kunkuntar ko kuma an toshe abin da zai sa a tilasta jini ya buga jini da sauri. Wannan saurin bugun zuciya da sauri yana haifar da matsanancin matsi a jijiyoyin jini.
Tadalafil foda yayi al'ajabi ta hanyar sassauta magudanan jini. Wannan shakatawa yana ba da damar gudan jini mai laushi don haka yana ƙaruwa da saurin gudu. Wannan yana taimakawa zuciya don tsotse jini mai laushi don haka ya taimaka matsi wanda in ba haka ba zai tara

Inganta ikon yin motsa jiki

A yayin motsa jiki gudan jini yana da mahimmanci don bawa mutum damar samun isashshen oxygen da kuma samar da isasshen kuzarin da ake buƙata.
Tadalafil na iya haɓaka aikin motsa jiki ta hanyar shakatawa sassan jijiyoyin ku da haɓaka yawo na jini.

Tasirin sakamako na Tadalafil

Mafi tasirin tasirin tadalafil sun hada da;

  • Ciwon kai,
  • Tashin zuciya,
  • flushing (zafi, redness, ko jin jiki),
  • ciki,
  • cunkoson hanci ko hanci, kuma
  • ciwon tsoka, ciwon baya, da zafi a cikin hannuwa ko ƙafafu.

Tadalafil na iya haifar da sakamako mai illa mai tsanani. An shawarce ku da ku nemi taimakon likita idan kun sami ɗayan waɗannan tasirin tasirin tadalafil masu zuwa;

  • wasu alamun cututtukan zuciya da suka haɗa da ciwon kirji, ciwo mai yaɗuwa zuwa muƙamuƙi ko kafaɗa, tashin zuciya, da gumi.
  • hangen nesa ya hada da gani mara kyau ko hangen nesa ba zato ba tsammani.
  • flushing (zafi, redness, ko jin jiki),
  • Rashin ji a ciki
  • ringing a cikin kunnuwa da rashin ji
  • Ginin da yake da zafi ko ya fi awanni 4 saboda wannan na iya lalata azzakarin ku.
  • Vomiting
  • Ƙwararren zuciya
  • Sumewa, jiri da,
  • Gajiya ta ban mamaki.

Hadin Kan Magunguna na Tadalafil

Yawancin rahoton hulɗar tadalafil tare da wasu magunguna an ba da rahoton. Hadin gwiwar magunguna yawanci yakan canza aikin magunguna kuma zai iya hana magungunan yin aiki yadda yakamata.
Don haka ana ba da shawara sosai don tattauna magungunan ku kafin ku yi amfani da tadalafil. Wasu hulɗar tadalafil na iya zama mai sauƙi da sauran mugu.
Da ke ƙasa akwai hulɗar tadalafil;

Nitrates

Ana kuma kiran su magungunan Anguina. Lokacin da aka ɗauki nitrates tare da tadalafil, zai iya haifar da saukar da hawan jini zuwa ƙananan matakan. Levelananan matakin karfin jini yana haɗuwa da alamomi kamar su jiri ko ma suma.
Wasu daga cikin wadannan magungunan anguina sun hada da; butyl nitrite, amyl nitrite, isosorbide dinitrate, nitroglycerin, da kuma isosorbide mononitrate.

Alpha-blockers

Wadannan kwayoyi ne da ake amfani dasu wajen gyara hawan jini. Ana amfani da su a maganin prostate. Duk masu tadalafil da alpha-blockers sune masu gyaran jiki wadanda ke da tasirin saukar karfin jini. Idan aka yi amfani dashi tare, zai iya haifar da raguwa / mahimmin digo a cikin jini. Wannan yana sa mutum ya zama mai hayaniya kuma yana iya suma.
Wasu daga cikin magungunan alpha-blockers sun hada da; terazosin, tamsulosin, alfuzosin, da prazosin.

Wasu magungunan HIV

Wadannan kwayoyi sune masu hana yaduwar kwayar cutar don haka zasu iya kara matakin tadalafil a cikin jini. Wannan haɓaka yana haifar da ƙananan jini. Hakanan yana iya haifar da fifiko ga maza wanda ke nufin sun sami tsayayyen gini wanda yakan zama mai zafi.
Wasu daga cikin waɗannan magungunan sune ritonavir da lopinavir.

Kwayoyi masu kare cututtuka

An ruwaito hulɗar Tadalafil tare da maganin rigakafi. Lokacin haɗuwa tare da tadalafil, maganin rigakafi na iya ƙara matakin tadalafil a cikin jini wanda ke haifar da saukar da hawan jini. Nasa na iya haifar da jiri, suma, har ma da wasu al'amura na hangen nesa. Hakanan yana iya haifar da fifiko ga maza.
Wasu daga cikin waɗannan kwayoyi sune erythromycin, telithromycin, da clarithromycin.
Koyaya, wasu maganin rigakafi na iya rage matakan tadalafil a cikin jini. Wadannan hulɗar tadalafil basa aiki yadda yakamata. Wadannan kwayoyi sun hada da; rifampin.

Magungunan antifungal

Wasu magungunan antifungal da suka hada da ketoconazole da itraconazole suna hulɗa da tadalafil.
Wadannan kwayoyi na iya tayar da matakin tadalafil wanda ke haifar da jiri da suma suma na iya faruwa.

Sauran magungunan hauhawar jini na huhu

Tadalafil da sauran magungunan hauhawar jini sanannu ne da samun tasirin rage karfin jini. Idan ana amfani dashi tare yana iya haifar da ƙananan matakan jini. Wannan yana haifar da ƙananan alamun alaƙa da alaƙa da jini kamar su jiri da suma.
Magungunan sun hada da riociguat.

Antacids

Ana amfani da waɗannan kwayoyi don taimakawa acid na ciki. Lokacin amfani dasu tare da tadalafil, zasu iya hana shayar tadalafil a cikin jiki. Sun hada da magnesium hydroxide ko aluminum hydroxide.

Magungunan farfadiya

Wadannan ana kiran su kwayoyi masu kama-karya. Lokacin da kuka ɗauki magungunan rigakafi tare da tadalafil, zasu iya rage shayar tadalafil. Wannan yana nufin cewa tadalafil ba zai iya yin aiki da kyau ba. Wadannan magungunan na farfadiya sun hada da phenytoin, phenobarbital, da carbamazepine.


Inda zan sayi Tadalafil?

Kuna iya sayan Tadalafil a shagunan kan layi. Ana samun foda a cikin yawa don masu bincike da manazarta. Tabbatar bincika tadalafil foda da aka yarda da masu samarwa.Lokacin da kayi la'akari da ɗaukar tadalafil saya shi daga amintattun masu sayarwa
Tuntuɓi likitan ku na likita kafin ɗaukar tadalafil saboda yiwuwar tasirin tasirin tadalafil da kuma hulɗar tadalafil tare da wasu magunguna.
Idan kuna neman Tadalafil ko matsakaitansa, yakamata ku bincika tare da CMOAPI don ingantaccen samfuran samfuran. Ma'aikatanmu sun sami tabbacin inganci.


References
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  3. "Cialis tadalafil PI". Gudanar da Kayayyakin Magunguna. An dawo da 2020-08-19.
  4. Karabakan M, Keskin E, Akdemir S, Bozkurt A (2017). Tasirin tadalafil 5mg magani na yau da kullun akan lokutan kawowa, ƙananan alamun urinary da aiki mai mahimmanci a cikin marasa lafiya tare da rashin aiki. International Braz j Urol: Jaridar hukuma ta Brazilianungiyar Urology ta Brazil. 2017 Mar-Apr; 43 (2): 317-324. DOI: 10.1590 / s1677-5538.ibju.2016.0376.
  5. "Pill Splitting" (PDF). Rahoton Abokan Ciniki. 2010-01-25. An adana daga asali (PDF) akan 2008-10-08.
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